{"id":3618,"date":"2020-09-08T09:09:39","date_gmt":"2020-09-08T09:09:39","guid":{"rendered":"https:\/\/www.editage.com\/insights\/novel-virus-based-colorimetric-sensor-can-show-true-colors-of-airborne-threats\/"},"modified":"2025-01-15T06:29:45","modified_gmt":"2025-01-15T06:29:45","slug":"novel-virus-based-colorimetric-sensor-can-show-true-colors-of-airborne-threats","status":"publish","type":"post","link":"https:\/\/www.editage.com\/insights\/novel-virus-based-colorimetric-sensor-can-show-true-colors-of-airborne-threats","title":{"rendered":"Novel virus-based colorimetric sensor can show true colors of airborne threats"},"content":{"rendered":"<p style=\"text-align:justify; margin:0in 0in 0.0001pt\"><span style=\"font-size:12pt\"><span style=\"text-justify:inter-ideograph\"><span style=\"font-family:&quot;Times New Roman&quot;,serif\"><span style=\"font-family:&quot;Calibri&quot;,sans-serif\">The ongoing COVID-19 pandemic has shown that the world needs technology that can quickly and accurately identify invisible dangers, including harmful substances or airborne environmental pollutants. Colorimetric sensors\u2014devices that intuitively reveal information about their environment through color changes\u2014are an attractive option in this regard. But, for more people to benefit from these sensors, they must be easy to produce at a large scale. This is a major limitation with currently available colorimetric sensors, which require complex structures with intricate fabrication procedures. Other problems with existing devices include slow response times and unsaturated colors.<\/span><\/span><\/span><\/span><\/p>\n<p style=\"text-align:justify; margin:0in 0in 0.0001pt\">\u00a0<\/p>\n<p style=\"text-align:justify; margin:0in 0in 0.0001pt\"><span style=\"font-size:12pt\"><span style=\"text-justify:inter-ideograph\"><span style=\"font-family:&quot;Times New Roman&quot;,serif\"><span style=\"font-family:&quot;Calibri&quot;,sans-serif\">Now in a new study published in <\/span><a href=\"http:\/\/dx.doi.org\/10.1002\/advs.202000978\" style=\"color:blue; text-decoration:underline\"><i><span style=\"font-family:&quot;Calibri&quot;,sans-serif\">Advanced Science<\/span><\/i><\/a><span style=\"font-family:&quot;Calibri&quot;,sans-serif\">,<\/span><span style=\"font-family:&quot;Calibri&quot;,sans-serif\"> scientists at Gwangju Institute of Science and Technology, Korea, have attempted to tackle these limitations by developing a new type of colorimetric sensor made up of a thin layer of viruses called<i> <\/i>M13 bacteriophages. They used this type of virus because it can change its<i> <\/i>structure\u2014and thus its optical properties\u2014in response to changes in the surrounding environment, such as the presence of harmful compounds. Prof Young Min Song, who led the study, explains, \u201c<i>In our study, we introduced the M13 bacteriophage, which is a nanometer-sized filamentous virus, as a sensing layer owing to its volumetrically expanding properties.<\/i>\u201d <\/span><\/span><\/span><\/span><\/p>\n<p style=\"text-align:justify; margin:0in 0in 0.0001pt\">\u00a0<\/p>\n<p style=\"text-align:justify; margin:0in 0in 0.0001pt\"><span style=\"font-size:12pt\"><span style=\"text-justify:inter-ideograph\"><span style=\"font-family:&quot;Times New Roman&quot;,serif\"><span style=\"font-family:&quot;Calibri&quot;,sans-serif\">The scientists genetically engineered the M13 bacteriophages by combining them with a \u201chighly lossy ultra-thin resonance promoter layer\u201d (HLRP) as the substrate. Then, they maximized the resonance of the coating layer of the viruses by optimizing the substrate such that the bacteriophage became extremely sensitive toward specific airborne substances. This made it possible for the \u201cviruses\u201d to <i>detect<\/i> chemicals at very low concentrations<\/span><span style=\"font-family:&quot;Calibri&quot;,sans-serif\">\u2014<\/span><span style=\"font-family:&quot;Calibri&quot;,sans-serif\">as low as tens of parts per billion. Prof Song explains the technique, \u201c<i>Specifically, through optimization of the virus layer deposition, the virus layer was coated with ultra-thin dimension, which enhanced the detection rate. The HLRP with resonance enhancement was applied to obtain a distinct color even with a nanometer-scale thickness change in the M13 bacteriophage virus layer. Consequently, the color change was maximized by optimized resonance conditions<\/i>.\u201d<\/span><\/span><\/span><\/span><\/p>\n<p style=\"text-align:justify; margin:0in 0in 0.0001pt\">\u00a0<\/p>\n<p style=\"text-align:justify; margin:0in 0in 0.0001pt\"><span style=\"font-size:12pt\"><span style=\"text-justify:inter-ideograph\"><span style=\"font-family:&quot;Times New Roman&quot;,serif\"><span style=\"font-family:&quot;Calibri&quot;,sans-serif\">The scientists tested the new sensor with environmental variables, like changes in humidity, and with compounds like volatile organic chemicals and endocrine disrupting chemicals. In both cases, changes in these stimuli could be successfully observed through distinct color changes in the sensor, thus showing its practical applicability. <\/span><\/span><\/span><\/span><\/p>\n<p style=\"text-align:justify; margin:0in 0in 0.0001pt\">\u00a0<\/p>\n<p style=\"text-align:justify; margin:0in 0in 0.0001pt\"><span style=\"font-size:12pt\"><span style=\"text-justify:inter-ideograph\"><span style=\"font-family:&quot;Times New Roman&quot;,serif\"><span style=\"font-family:&quot;Calibri&quot;,sans-serif\">This new design for highly effective and mass-producible colorimetric sensor holds much promise for a variety of real-life applications, such as detecting harmful industrial chemicals or assessing air quality. To top it all, these sensors could become invaluable tools in clinical settings, as Prof Song remarks, \u201c<i>In the future, advances in genetic engineering will enhance the sensitivity of the sensors and extend their applicability to the medical industry, where they could be used as diagnostic kits for detecting specific viruses and pathogens.<\/i>\u201d<\/span><\/span><\/span><\/span><\/p>\n<p style=\"text-align:justify; margin:0in 0in 0.0001pt\">\u00a0<\/p>\n<p style=\"text-align:justify; margin:0in 0in 0.0001pt\"><span style=\"font-size:12pt\"><span style=\"text-justify:inter-ideograph\"><span style=\"font-family:&quot;Times New Roman&quot;,serif\"><span style=\"font-family:&quot;Calibri&quot;,sans-serif\">With further research, this technology will hopefully work as a powerful means to show <i>the true colors<\/i> of invisible airborne threats.<\/span><\/span><\/span><\/span><\/p>\n<p style=\"margin:0in 0in 0.0001pt\">\u00a0<\/p>\n<p style=\"margin:0in 0in 0.0001pt\"><strong>Reference<\/strong><\/p>\n<p align=\"center\" style=\"text-align:center; margin:0in 0in 0.0001pt\">\u00a0<\/p>\n<p style=\"margin:0in 0in 0.0001pt\"><span style=\"font-size:12pt\"><span style=\"tab-stops:106.35pt\"><span style=\"font-family:&quot;Times New Roman&quot;,serif\"><span style=\"font-family:&quot;Calibri&quot;,sans-serif\"><strong>Authors<\/strong>: <\/span><span style=\"font-family:&quot;Calibri&quot;,sans-serif\">Young Jin Yoo (1), Won-Geun Kim (2), Joo Hwan Ko (1), Yeong Jae Kim (1), Yujin Lee (2), Stefan G. Stanciu (3), Jong-Min Lee (4), Seungchul Kim (5), Jin-Woo Oh (<\/span><span style=\"font-family:&quot;Calibri&quot;,sans-serif\">2<\/span><span style=\"font-family:&quot;Calibri&quot;,sans-serif\">), and Young Min Song (1*)<\/span><\/span><\/span><\/span><\/p>\n<p style=\"margin:0in 0in 0.0001pt\">\u00a0<\/p>\n<p style=\"margin:0in 0in 0.0001pt\"><span style=\"font-size:12pt\"><span style=\"tab-stops:106.35pt\"><span style=\"font-family:&quot;Times New Roman&quot;,serif\"><span style=\"font-family:&quot;Calibri&quot;,sans-serif\"><strong>Title of original paper<\/strong>: Large-Area Virus Coated Ultrathin Colorimetric Sensors with a Highly Lossy Resonant Promoter for Enhanced Chromaticity<\/span><\/span><\/span><\/span><\/p>\n<p style=\"margin:0in 0in 0.0001pt\">\u00a0<\/p>\n<p style=\"margin:0in 0in 0.0001pt\"><span style=\"font-size:12pt\"><span style=\"tab-stops:106.35pt\"><span style=\"font-family:&quot;Times New Roman&quot;,serif\"><span style=\"font-family:&quot;Calibri&quot;,sans-serif\"><strong>Journal<\/strong>: <i>Advanced Science<\/i><\/span><\/span><\/span><\/span><\/p>\n<p style=\"margin:0in 0in 0.0001pt\">\u00a0<\/p>\n<p style=\"margin:0in 0in 0.0001pt\"><span style=\"font-size:12pt\"><span style=\"tab-stops:106.35pt\"><span style=\"font-family:&quot;Times New Roman&quot;,serif\"><span style=\"font-family:&quot;Calibri&quot;,sans-serif\"><strong>DOI<\/strong>: <\/span><span style=\"font-family:&quot;Calibri&quot;,sans-serif\"><a href=\"http:\/\/dx.doi.org\/10.1002\/advs.202000978\" style=\"color:blue; text-decoration:underline\">10.1002\/advs.202000978<\/a><\/span><\/span><\/span><\/span><\/p>\n<p style=\"margin:0in 0in 0.0001pt\">\u00a0<\/p>\n<p style=\"margin:0in 0in 0.0001pt\"><span style=\"font-size:12pt\"><span style=\"font-family:&quot;Times New Roman&quot;,serif\"><span style=\"font-family:&quot;Calibri&quot;,sans-serif\"><strong>Affiliations<\/strong>:<\/span><\/span><\/span><\/p>\n<p style=\"margin:0in 0in 0.0001pt\"><span style=\"font-size:12pt\"><span style=\"font-family:&quot;Times New Roman&quot;,serif\"><span style=\"font-family:&quot;Calibri&quot;,sans-serif\">(1) School of Electrical Engineering and Computer Science, Gwangju Institute of Science and Technology<\/span><\/span><\/span><\/p>\n<p style=\"margin:0in 0in 0.0001pt\"><span style=\"font-size:12pt\"><span style=\"font-family:&quot;Times New Roman&quot;,serif\"><span style=\"font-family:&quot;Calibri&quot;,sans-serif\">(2) Department of Nano Fusion Technology, Pusan National University<\/span><\/span><\/span><\/p>\n<p style=\"margin:0in 0in 0.0001pt\"><span style=\"font-size:12pt\"><span style=\"font-family:&quot;Times New Roman&quot;,serif\"><span style=\"font-family:&quot;Calibri&quot;,sans-serif\">(3) Center for Microscopy-Microanalysis and Information Processing, Politehnica University Bucharest<\/span><\/span><\/span><\/p>\n<p style=\"margin:0in 0in 0.0001pt\"><span style=\"font-size:12pt\"><span style=\"font-family:&quot;Times New Roman&quot;,serif\"><span style=\"font-family:&quot;Calibri&quot;,sans-serif\">(4) Research Center for Energy Convergence and Technology, Pusan National University<\/span><\/span><\/span><\/p>\n<p style=\"margin:0in 0in 0.0001pt\"><span style=\"font-size:12pt\"><span style=\"font-family:&quot;Times New Roman&quot;,serif\"><span style=\"font-family:&quot;Calibri&quot;,sans-serif\">(5) Department of Optics and Mechatronics Engineering, Pusan National University<\/span><\/span><\/span><\/p>\n<p style=\"margin:0in 0in 0.0001pt\">\u00a0<\/p>\n<p style=\"margin:0in 0in 0.0001pt\"><span style=\"font-size:12pt\"><span style=\"font-family:&quot;Times New Roman&quot;,serif\"><span style=\"font-family:&quot;Calibri&quot;,sans-serif\">*Corresponding author\u2019s\u00a0emails: <span class=\"MsoHyperlink\" style=\"color:blue\"><span style=\"text-decoration:underline\"><a href=\"mailto:ymsong@gist.ac.kr\" style=\"color:blue; text-decoration:underline\">ymsong@gist.ac.kr<\/a><\/span><\/span> (Y. M. Song)<\/span><\/span><\/span><\/p>\n<p style=\"margin:0in 0in 0.0001pt\">\u00a0<\/p>\n<p style=\"text-align:justify; margin:0in 0in 0.0001pt\"><span style=\"font-size:12pt\"><span style=\"font-family:Calibri,sans-serif\"><span style=\"color:black\"><b>About Gwangju Institute of Science and Technology (GIST) <\/b><\/span><\/span><\/span><\/p>\n<p class=\"Default\" style=\"margin:0in 0in 0.0001pt\"><span style=\"font-size:12pt\"><span style=\"text-justify:inter-ideograph\"><span style=\"font-family:&quot;Times New Roman&quot;,serif\"><span style=\"font-family:&quot;Calibri&quot;,sans-serif\"><a href=\"http:\/\/www.gist.ac.kr\/\">Gwangju Institute of Science and Technology<\/a> (GIST) is a research-oriented university situated in Gwangju, South Korea. One of the most prestigious schools in South Korea, it was founded in 1993.<span style=\"background:white\"> The university aims to create a strong research environment to spur advancements in science and technology and to promote collaboration between foreign and domestic research programs<\/span>. With its motto, \u201cA Proud Creator of Future Science and Technology,\u201d the university has consistently received one of the highest university rankings in Korea. <\/span><\/span><\/span><\/span><\/p>\n<p style=\"text-align:justify; margin:0in 0in 0.0001pt\">\u00a0<\/p>\n<p class=\"Default\" style=\"margin:0in 0in 0.0001pt\"><span style=\"font-size:12pt\"><span style=\"font-family:Calibri,sans-serif\"><span style=\"color:black\"><b>About the author<\/b><\/span><\/span><\/span><\/p>\n<p class=\"Default\" style=\"margin:0in 0in 0.0001pt\"><span style=\"font-size:12pt\"><span style=\"text-justify:inter-ideograph\"><span style=\"font-family:Calibri,sans-serif\"><span style=\"color:black\">Young Min Song completed his PhD degree in Information and Communications from Gwangju Institute of Science and Technology (GIST) in 2011. From 2011 to 2013, he was a postdoctoral research associate in the Department of Materials Science and Engineering at the University of Illinois, USA, at Urbana\u2013Champaign (UIUC). He is currently an Associate Professor in the School of Electrical Engineering and Computer Science at GIST. His group is currently working on developing advanced optoelectronic sensors\/systems, multifunctional nanophotonics, and optical healthcare systems. Over the past few decades, he has focused developing bio-inspired optoelectronic sensors.<\/span><\/span><\/span><\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>The ongoing COVID-19 pandemic has shown that the world needs technology that can quickly and accurately identify invisible dangers, including harmful substances or airborne environmental pollutants. Colorimetric sensors\u2014devices that intuitively reveal information about their environment through color changes\u2014are an attractive option in this regard. But, for more people to benefit from these sensors, they must [&hellip;]<\/p>\n","protected":false},"author":1152,"featured_media":33313,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"categories":[2435],"tags":[2482],"new_categories":[],"new_tags":[],"series":[],"class_list":["post-3618","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-trending-research","tag-science-update"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v25.0 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Novel virus-based colorimetric sensor can show true colors of airborne threats | Editage Insights<\/title>\n<meta name=\"description\" content=\"Scientists employ genetically engineered viruses to produce intuitive color-coded sensors for detecting airborne chemicals\" \/>\n<meta name=\"robots\" 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