{"id":17984,"date":"2013-11-25T11:07:56","date_gmt":"2013-11-25T11:07:56","guid":{"rendered":"https:\/\/www.editage.com\/insights\/research\/does-antiviral-rna-interference-exist-in-mammalian-cells\/"},"modified":"2025-09-19T15:57:43","modified_gmt":"2025-09-19T10:27:43","slug":"does-antiviral-rna-interference-exist-in-mammalian-cells","status":"publish","type":"research","link":"https:\/\/www.editage.com\/insights\/does-antiviral-rna-interference-exist-in-mammalian-cells","title":{"rendered":"Does antiviral RNA interference exist in mammalian cells?"},"content":{"rendered":"<p style=\"text-align: justify;\"><span style=\"font-family: verdana,geneva,sans-serif;\"><span style=\"font-size: 14px;\"><span style=\"color: #111111; line-height: 19.09090805053711px; text-align: justify;\">Long thought to have been eliminated in mammals, antiviral RNA interference may exist in mammalian cells, after all, suggest Maillard et al.\u00a0<\/span>They studied the embryonic stem cells from mice and found that the mice used RNA cells to defend themselves from infection, confirming the presence of antiviral mechanism. This study has become a topic of much debate among researchers worldwide.\u00a0<span style=\"color: #111111; line-height: 17.27272605895996px; text-align: justify;\">Read more in\u00a0<\/span><u style=\"font-family: verdana, geneva, sans-serif; font-size: 14px; color: #111111; line-height: 17.27272605895996px; text-align: justify; box-sizing: border-box;\"><a style=\"box-sizing: border-box; color: #1b609a;\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24115438?dopt=Abstract&amp;holding=npg\" target=\"_blank\" rel=\"noopener\"><em style=\"box-sizing: border-box;\">Science<\/em><\/a><\/u><span style=\"color: #111111; line-height: 17.27272605895996px; text-align: justify;\">.<\/span><\/span><\/span><\/p>\n<p style=\"box-sizing: border-box; margin: 0px 0px 1em; line-height: 17.27272605895996px; color: #111111; font-family: Arial, Helvetica, sans-serif; font-size: 12.727272033691406px; text-align: justify;\"><span style=\"font-family: verdana,geneva,sans-serif;\"><span style=\"font-size: 14px;\"><span style=\"box-sizing: border-box;\"><span style=\"box-sizing: border-box;\">PV Maillard et al.,\u00a0<em style=\"box-sizing: border-box;\">Science<\/em>, 2013; 342. DOI: 10.1126\/science.1241930<\/span><\/span><\/span><\/span><\/p>\n","protected":false},"author":8,"featured_media":33313,"template":"","meta":{"_acf_changed":false,"inline_featured_image":false},"new_tags":[],"series":[],"subject":[2976,2974,2975],"class_list":["post-17984","research","type-research","status-publish","has-post-thumbnail","hentry","subject-and-molecular-biology","subject-biochemistry","subject-genetics"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v25.0 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Does Antiviral RNA Interference Exist in Mammalian Cells | Editage Insights<\/title>\n<meta name=\"description\" content=\"Antiviral RNA interference may exist in mammalian cells which was thought to have been eliminated in mammals, suggested by Maillard et al.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.editage.com\/insights\/does-antiviral-rna-interference-exist-in-mammalian-cells\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Does Antiviral RNA Interference Exist in Mammalian Cells | Editage Insights\" \/>\n<meta property=\"og:description\" content=\"Antiviral RNA interference may exist in mammalian cells which was thought to have been eliminated in mammals, suggested by Maillard et al.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.editage.com\/insights\/does-antiviral-rna-interference-exist-in-mammalian-cells\" \/>\n<meta property=\"og:site_name\" content=\"Editage Insights\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/Editage\" \/>\n<meta property=\"article:modified_time\" content=\"2025-09-19T10:27:43+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.editage.com\/insights\/wp-content\/uploads\/2025\/06\/editage-insights-generic-banner.png\" \/>\n\t<meta property=\"og:image:width\" content=\"870\" \/>\n\t<meta property=\"og:image:height\" content=\"446\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:site\" content=\"@Editage\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.editage.com\/insights\/does-antiviral-rna-interference-exist-in-mammalian-cells\",\"url\":\"https:\/\/www.editage.com\/insights\/does-antiviral-rna-interference-exist-in-mammalian-cells\",\"name\":\"Does Antiviral RNA Interference Exist in Mammalian Cells | Editage Insights\",\"isPartOf\":{\"@id\":\"https:\/\/www.editage.com\/insights\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/www.editage.com\/insights\/does-antiviral-rna-interference-exist-in-mammalian-cells#primaryimage\"},\"image\":{\"@id\":\"https:\/\/www.editage.com\/insights\/does-antiviral-rna-interference-exist-in-mammalian-cells#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.editage.com\/insights\/wp-content\/uploads\/2025\/02\/editage-insights-generic-banner_298.webp\",\"datePublished\":\"2013-11-25T11:07:56+00:00\",\"dateModified\":\"2025-09-19T10:27:43+00:00\",\"description\":\"Antiviral RNA interference may exist in mammalian cells which was thought to have been eliminated in mammals, suggested by Maillard et al.\",\"breadcrumb\":{\"@id\":\"https:\/\/www.editage.com\/insights\/does-antiviral-rna-interference-exist-in-mammalian-cells#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.editage.com\/insights\/does-antiviral-rna-interference-exist-in-mammalian-cells\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.editage.com\/insights\/does-antiviral-rna-interference-exist-in-mammalian-cells#primaryimage\",\"url\":\"https:\/\/www.editage.com\/insights\/wp-content\/uploads\/2025\/02\/editage-insights-generic-banner_298.webp\",\"contentUrl\":\"https:\/\/www.editage.com\/insights\/wp-content\/uploads\/2025\/02\/editage-insights-generic-banner_298.webp\",\"width\":656,\"height\":336},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.editage.com\/insights\/does-antiviral-rna-interference-exist-in-mammalian-cells#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/www.editage.com\/insights\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Researchs\",\"item\":\"https:\/\/www.editage.com\/insights\/research\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Does antiviral RNA interference exist in mammalian cells?\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.editage.com\/insights\/#website\",\"url\":\"https:\/\/www.editage.com\/insights\/\",\"name\":\"Editage Insights\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\/\/www.editage.com\/insights\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.editage.com\/insights\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.editage.com\/insights\/#organization\",\"name\":\"Editage Insights\",\"url\":\"https:\/\/www.editage.com\/insights\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.editage.com\/insights\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/www.editage.com\/insights\/wp-content\/uploads\/2024\/09\/editage-insights-logo-1-scaled.webp\",\"contentUrl\":\"https:\/\/www.editage.com\/insights\/wp-content\/uploads\/2024\/09\/editage-insights-logo-1-scaled.webp\",\"width\":2560,\"height\":324,\"caption\":\"Editage Insights\"},\"image\":{\"@id\":\"https:\/\/www.editage.com\/insights\/#\/schema\/logo\/image\/\"},\"sameAs\":[\"https:\/\/www.facebook.com\/Editage\",\"https:\/\/x.com\/Editage\"]}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Does Antiviral RNA Interference Exist in Mammalian Cells | Editage Insights","description":"Antiviral RNA interference may exist in mammalian cells which was thought to have been eliminated in mammals, suggested by Maillard et al.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.editage.com\/insights\/does-antiviral-rna-interference-exist-in-mammalian-cells","og_locale":"en_US","og_type":"article","og_title":"Does Antiviral RNA Interference Exist in Mammalian Cells | Editage Insights","og_description":"Antiviral RNA interference may exist in mammalian cells which was thought to have been eliminated in mammals, suggested by Maillard et al.","og_url":"https:\/\/www.editage.com\/insights\/does-antiviral-rna-interference-exist-in-mammalian-cells","og_site_name":"Editage Insights","article_publisher":"https:\/\/www.facebook.com\/Editage","article_modified_time":"2025-09-19T10:27:43+00:00","og_image":[{"width":870,"height":446,"url":"https:\/\/www.editage.com\/insights\/wp-content\/uploads\/2025\/06\/editage-insights-generic-banner.png","type":"image\/png"}],"twitter_card":"summary_large_image","twitter_site":"@Editage","twitter_misc":{"Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.editage.com\/insights\/does-antiviral-rna-interference-exist-in-mammalian-cells","url":"https:\/\/www.editage.com\/insights\/does-antiviral-rna-interference-exist-in-mammalian-cells","name":"Does Antiviral RNA Interference Exist in Mammalian Cells | Editage Insights","isPartOf":{"@id":"https:\/\/www.editage.com\/insights\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.editage.com\/insights\/does-antiviral-rna-interference-exist-in-mammalian-cells#primaryimage"},"image":{"@id":"https:\/\/www.editage.com\/insights\/does-antiviral-rna-interference-exist-in-mammalian-cells#primaryimage"},"thumbnailUrl":"https:\/\/www.editage.com\/insights\/wp-content\/uploads\/2025\/02\/editage-insights-generic-banner_298.webp","datePublished":"2013-11-25T11:07:56+00:00","dateModified":"2025-09-19T10:27:43+00:00","description":"Antiviral RNA interference may exist in mammalian cells which was thought to have been eliminated in mammals, suggested by Maillard et al.","breadcrumb":{"@id":"https:\/\/www.editage.com\/insights\/does-antiviral-rna-interference-exist-in-mammalian-cells#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.editage.com\/insights\/does-antiviral-rna-interference-exist-in-mammalian-cells"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.editage.com\/insights\/does-antiviral-rna-interference-exist-in-mammalian-cells#primaryimage","url":"https:\/\/www.editage.com\/insights\/wp-content\/uploads\/2025\/02\/editage-insights-generic-banner_298.webp","contentUrl":"https:\/\/www.editage.com\/insights\/wp-content\/uploads\/2025\/02\/editage-insights-generic-banner_298.webp","width":656,"height":336},{"@type":"BreadcrumbList","@id":"https:\/\/www.editage.com\/insights\/does-antiviral-rna-interference-exist-in-mammalian-cells#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.editage.com\/insights\/"},{"@type":"ListItem","position":2,"name":"Researchs","item":"https:\/\/www.editage.com\/insights\/research"},{"@type":"ListItem","position":3,"name":"Does antiviral RNA interference exist in mammalian cells?"}]},{"@type":"WebSite","@id":"https:\/\/www.editage.com\/insights\/#website","url":"https:\/\/www.editage.com\/insights\/","name":"Editage Insights","description":"","publisher":{"@id":"https:\/\/www.editage.com\/insights\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.editage.com\/insights\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/www.editage.com\/insights\/#organization","name":"Editage Insights","url":"https:\/\/www.editage.com\/insights\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.editage.com\/insights\/#\/schema\/logo\/image\/","url":"https:\/\/www.editage.com\/insights\/wp-content\/uploads\/2024\/09\/editage-insights-logo-1-scaled.webp","contentUrl":"https:\/\/www.editage.com\/insights\/wp-content\/uploads\/2024\/09\/editage-insights-logo-1-scaled.webp","width":2560,"height":324,"caption":"Editage Insights"},"image":{"@id":"https:\/\/www.editage.com\/insights\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/Editage","https:\/\/x.com\/Editage"]}]}},"_links":{"self":[{"href":"https:\/\/www.editage.com\/insights\/wp-json\/wp\/v2\/research\/17984","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.editage.com\/insights\/wp-json\/wp\/v2\/research"}],"about":[{"href":"https:\/\/www.editage.com\/insights\/wp-json\/wp\/v2\/types\/research"}],"author":[{"embeddable":true,"href":"https:\/\/www.editage.com\/insights\/wp-json\/wp\/v2\/users\/8"}],"version-history":[{"count":0,"href":"https:\/\/www.editage.com\/insights\/wp-json\/wp\/v2\/research\/17984\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.editage.com\/insights\/wp-json\/wp\/v2\/media\/33313"}],"wp:attachment":[{"href":"https:\/\/www.editage.com\/insights\/wp-json\/wp\/v2\/media?parent=17984"}],"wp:term":[{"taxonomy":"new_tags","embeddable":true,"href":"https:\/\/www.editage.com\/insights\/wp-json\/wp\/v2\/new_tags?post=17984"},{"taxonomy":"series","embeddable":true,"href":"https:\/\/www.editage.com\/insights\/wp-json\/wp\/v2\/series?post=17984"},{"taxonomy":"subject","embeddable":true,"href":"https:\/\/www.editage.com\/insights\/wp-json\/wp\/v2\/subject?post=17984"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}