{"id":18130,"date":"2016-07-05T16:01:44","date_gmt":"2016-07-05T16:01:44","guid":{"rendered":"https:\/\/www.editage.com\/insights\/research\/can-e-coli-be-used-to-transport-vaccines\/"},"modified":"2025-09-22T11:50:06","modified_gmt":"2025-09-22T06:20:06","slug":"can-e-coli-be-used-to-transport-vaccines","status":"publish","type":"research","link":"https:\/\/www.editage.com\/insights\/can-e-coli-be-used-to-transport-vaccines","title":{"rendered":"Can E. coli be used to transport vaccines?"},"content":{"rendered":"<p style=\"text-align: justify;\"><span style=\"font-size: 14px;\">A team of researchers from the University of Buffalo have developed an E. coli based capsule, which according to them, can transport vaccines more efficiently than the currently available immunizations. While most people fear E. coli, the study\u2019s co-lead author\u00a0Blaine A. Pfeifer, PhD, associate professor of chemical and biological engineering in the University at Buffalo School of Engineering and Applied Sciences says that \u201cthere are many strains of the bacteria, most of which are perfectly normal in the body, that have great potential to fight disease.\u201d The team used harmless E. coli as the core of the transport capsule. This capsule was created by wrapping beta amino ester \u2013 a synthetic polymer \u2013 around the bacteria, which is positively charged. When it combined with the negatively charged bacteria cell wall, a hybrid capsule was created. To test it, they inserted in it a protein-based vaccine to fight pneumococcal disease and found that the capsule triggered an immune response in mice and protected them against pneumococcal disease. Pfiefer is attempting to commercialize this relatively inexpensive biotechnology since it can be used to as a delivery device in treatments targeting cancer and viral diseases. \u00a0<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 14px;\">Read more in <em><a href=\"https:\/\/www.sciencedaily.com\/releases\/2016\/07\/160701183554.htm\">Science Daily<\/a><\/em>.<\/span><\/p>\n","protected":false},"author":8,"featured_media":33313,"template":"","meta":{"_acf_changed":false,"inline_featured_image":false},"new_tags":[],"series":[],"subject":[2976,2974,2975],"class_list":["post-18130","research","type-research","status-publish","has-post-thumbnail","hentry","subject-and-molecular-biology","subject-biochemistry","subject-genetics"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v25.0 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Can E. coli be used to transport vaccines? | Editage Insights<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.editage.com\/insights\/can-e-coli-be-used-to-transport-vaccines\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Can E. coli be used to transport vaccines? | Editage Insights\" \/>\n<meta property=\"og:description\" content=\"A team of researchers from the University of Buffalo have developed an E. coli based capsule, which according to them, can transport vaccines more efficiently than the currently available immunizations. 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