{"id":18360,"date":"2015-07-07T07:00:28","date_gmt":"2015-07-07T07:00:28","guid":{"rendered":"https:\/\/www.editage.com\/insights\/research\/researchers-unravel-a-3-d-map-of-capsid-protein\/"},"modified":"2025-09-22T10:49:32","modified_gmt":"2025-09-22T05:19:32","slug":"researchers-unravel-a-3-d-map-of-capsid-protein","status":"publish","type":"research","link":"https:\/\/www.editage.com\/insights\/researchers-unravel-a-3-d-map-of-capsid-protein","title":{"rendered":"Researchers unravel a 3-D map of capsid protein"},"content":{"rendered":"<p style=\"text-align: justify;\"><span style=\"font-size: 14px;\">Researchers at the University of Missouri have been able to procure detailed images of the capsid protein, which is a key protein in HIV, in its natural state. Stefan Sarafianos \u2013 an associate professor of molecular microbiology and immunology and the Chancellor&#8217;s Chair of Excellence in molecular virology in the University of Missouri School of Medicine \u2013 who is heading the team of researchers, explains, \u201cThe capsid shell acts as an &#8216;invisibility cloak&#8217; that hides the virus&#8217; genetic information, the genome, while it is being copied in a hostile environment for the virus.\u201d Using a technique called X-ray crystallography, Sarafianos and his team created the most complete model yet of an HIV capsid protein and developed the protein\u2019s 3-D map. The model revealed that the protein consists of water molecules, which help the capsid shell to be flexible and assume different forms, a critical requirement for the life cycle of the HIV virus. This model of the capsid protein will help in the development of antiviral drugs that combat HIV and AIDS.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 14px;\">Read more in <a href=\"http:\/\/www.sciencedaily.com\/releases\/2015\/07\/150701093856.htm\"><em>Science Daily<\/em><\/a>.\u00a0<\/span><\/p>\n","protected":false},"author":8,"featured_media":33313,"template":"","meta":{"_acf_changed":false,"inline_featured_image":false},"new_tags":[],"series":[],"subject":[2976,2974,2975],"class_list":["post-18360","research","type-research","status-publish","has-post-thumbnail","hentry","subject-and-molecular-biology","subject-biochemistry","subject-genetics"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v25.0 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Researchers unravel a 3-D map of capsid protein | Editage Insights<\/title>\n<meta name=\"description\" content=\"Researchers at the University of Missouri have been able to procure detailed images of the capsid protein, which is a key protein in HIV, in its natural state. 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