Artificial sweeteners linked to obesity and metabolic disorders

Artificial sweeteners linked to obesity and metabolic disorders

A joint team headed by Eran Segal and Eran Elinav of the Weizmann Institute of Science in Rehovot led a study that found links between the use of sugar substitutes such as saccharine and obesity. It is also the first study to suggest that sweeteners cause metabolic disorders when they are exposed to the gut microbiome—the diverse community of bacteria in the human intestines. The researchers studied the effects of sweetener consumption on mice and found that the mice became glucose intolerant. To check whether the sweeteners were affecting the murine microbiome, the researchers used antibiotics to kill the gut bacteria, which reversed the metabolic changes, suggesting that artificial sweeteners were making microbiome unhealthy. The researchers then studied the effect of sweeteners on healthy human volunteers. While some became glucose intolerant and showed susceptibility to metabolic diseases, others did not. This indicates that the generic use of sweeteners should be avoided. However, more research is required to draw any firm conclusions.

Read more in Nature

You're looking to give wings to your academic career and publication journey. We like that!

Why don't we give you complete access! Create a free account and get unlimited access to all resources & a vibrant researcher community.

One click sign-in with your social accounts

234 visitors saw this today and 223 signed up.

Found this useful?

If so, share it with your fellow researchers